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SPRAVATO® (Esketamine) Treatment

Say Hello to a New You

Spravato is a medication that works differently from traditional antidepressants by targeting a specific pathway in the brain. It blocks a (NMDA) receptor that affects how certain brain chemicals, like glutamate, interact to maintain mood balance. This process helps create new connections between brain cells and improves the brain's ability to adapt and change, which can help reduce symptoms of depression.

History of Spravato​:

In 2019, the FDA granted approval for SPRAVATO®, an esketamine-derived nasal spray designed for adults grappling with Treatment Resistant Depression and suicidal ideation. This significant milestone reinforces the medical community’s confidence in the potency of the Ketamine molecule, showcasing its capability to deliver substantial and prompt relief. This nasal spray represents a new frontier in treatment options, providing hope and possibilities for those navigating the complexities of depression. Esketamine plus an oral antidepressant has been found to relieve the symptoms of depression within hours, rather than the usual weeks most antidepressants can take.

Is Spravato Right For You?

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  • You’ve tried many options over the years and can’t seem to find relief from your depression and have been diagnosed with Major Depressive Disorder

  • You have suicidal ideation 

Your Spravato Treatment Journey at Lumos Mental Health 

Taking SPRAVATO® nasal spray is a straightforward process, conducted under the supervision of our healthcare professionals in a comfortable healthcare setting. Here’s what you can expect:

Evaluation

Your journey at Lumos Mental Health begins with an evaluation with our psychiatric medical provider. During this appointment the provider will inquire about your medical and mental health treatment history including medications, treatments and symptoms. If you meet the criteria for Spravato the provider will recommend you for treatment. Once a complete history is gathered, your provider will lay out the options, and together you will create the plan to move forward.

Monitoring and Support

Throughout your Spravato session, our healthcare team will closely monitor your well-being. Clients are monitored to see real time blood pressure, heart rate, and oxygen saturation measurements.

 

We’ll assess your readiness to leave the healthcare setting after each use.

Pre-Authorization

​Personalized Treatment Plan

Insurance covers Spravato in most cases but does require pre-authorization from your insurance carrier prior to beginning treatment. This process can take time to complete.

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Once approved, the path to a new you begins!

 

Your provider will determine the appropriate dosage and schedule for your Spravato treatment. Each session lasts about 2 hours. You will self-administer Spravato, following the instructions provided by our provider.

 

They will demonstrate the proper technique for using the nasal spray device. 
 

Adherence to Guidelines

To minimize the risk of side effects, it’s crucial to follow specific guidelines, such as refraining from eating for at least four hours before using Spravato and avoiding liquids for at least 30 minutes prior. You will discuss these guidelines with your provider prior to your appointment.

Medication Interaction

If you’re taking nasal corticosteroids or nasal decongestants, ensure you take these medications at least one hour before using SPRAVATO® to prevent potential interactions. 

 

Please discuss with your provider prior to your appointment.

What To Expect

Clients are closely observed and monitored by our staff throughout treatment to help ensure a safe and comfortable experience. During each session, our team carefully monitors vital signs, including blood pressure, heart rate, and oxygen saturation, while providing ongoing support and attention to each patient's needs.

You may experience temporary side effects:

  • Sedation

  • Dissociation (including out-of-body experience, distortion of time and space, illusions, derealization)

  • Dizziness

  • Nausea (we have medication available to help with this)

  • Increased Blood Pressure

  • Hypoesthesia (loss of sensation in a body part)

  • Cognitive Impairment (reduced attention, judgment, thinking, reaction speed and motor skills)

 

You will be ready to go home after our medical provider clears you for release. You cannot drive home, so please secure a ride with a friend or family member.

At Lumos Mental Health, your comfort, safety, and well-being are paramount. Our experienced providers are dedicated to supporting you throughout your Spravato treatment journey.

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Watch Video: What to Expect During Your SPRAVATO® Treatment

Insurance Coverage

Insurance coverage for Spravato can vary significantly depending on you specific plan and policy. There are two ways that Spravato may be covered under a patient’s insurance plan.

1. Medical Benefits: Some insurance plans cover Spravato as a part of your Medical benefits.

2. Pharmacy Plan: Alternatively, it may be covered under your pharmacy benefits.

 

Since Spravato requires administration by a healthcare professional and 2-hour monitoring, there are two billing aspects:

1. Medication Cost: This includes the cost of the medication itself, which can be covered through pharmacy or medical benefits.

2. Clinical Monitoring: The 2-hour observation and monitoring by our clinical team.

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At Lumos Mental Health, we conduct a through investigation of each clients insurance plan and benefits to determine coverage and any potential out-of-pocket cost. Clients will receive an estimated expected out-of-pocket cost before starting treatment. Additionally, we assist patients in exploring options, including the Spravato withME program, which helps reduce cost for those with no insurance coverage or lower out-of-pocket expenses.

Measurable relief that lasts

            70%                       52%                  5               30,000

            Of clients experienced           of clients achieved remission      Years of potential depression        Patients have received 

      measurable relief of symptoms.                 after 4 weeks.                            symptom relief.                    treatment in the U.S. 

 


 

Client Testimonies
Real stories. Real experiences. Discover how Spravato treatment has helped patients take meaningful steps toward healing.

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